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Associate Researcher
shlomit.beker@einsteinmed.edu
Dr. Beker holds a PhD in neurophysiology and MsC in Cognitive Psychology. She investigates the oscillatory signatures in normal vs. abnormal information processing. Dr. Beker's current research is focused on probing the neuronal dynamics underlying inflexibility in people with Autism Spectrum Disorder (ASD). In this framework, the processes of interest are the ability of individuals with ASD to make temporal predictions upon their environment, and to be adaptive to novel stimuli and patterns. This is achieved through EEG measurements of the temporal dynamics critical in normal functioning, as well as through pupillometry and psychophysics.
Here's a short video where Dr. Beker explains her study
Publications
Beker S, Foxe JJ, Molholm S. (2018). Ripe for solution: Delayed development of multisensory processing in autism and its remediation. Neurosci Biobehav Rev. 2018 Jan;84:182-192. doi: 10.1016/j.neubiorev.2017.11.008. Epub 2017 Nov 21. Review.
Beker S, Kellner V, Chechik G, Stern EA. (2016) Learning to classify neural activity from a mouse model of Alzheimer's disease amyloidosis versus controls. Alzheimers Dement (Amst). 2016 Feb 3;2:39-48. doi: 10.1016/j.dadm.2016.01.002.
Beker S, Goldin M, Menkes-Caspi N, Kellner V, Chechik G, Stern EA. (2016). Amyloid-β disrupts ongoing spontaneous activity in sensory cortex. Brain Struct Funct. 2016 Mar;221(2):1173-88. doi: 10.1007/s00429-014-0963-x. Epub 2014 Dec 19.
Kellner V, Menkes-Caspi N, Beker S, Stern EA. (2014). Amyloid-β alters ongoing neuronal activity and excitability in the frontal cortex. Neurobiol Aging. 2014 Sep;35(9):1982-91. doi: 10.1016/j.neurobiolaging.2014.04.001.
Beker S, Kellner V, Kerti L, Stern EA. (2012). Interaction between amyloid-β pathology and cortical functional columnar organization. J Neurosci. 2012 Aug 15;32(33):11241-9. doi: 10.1523/JNEUROSCI.2426-12.2012.
Primary paper in Alzforum.org.
A review and an interview: Barreling Down Amyloid Plaque Distribution