Sophie Molholm, Ph.D
Director of the CNL & the HCP
sophie.molholm@einsteinmed.edu
Dr. Sophie Molholm is Professor in the Departments of Pediatrics, Neuroscience, and Psychiatry. She is director of the Cognitive Neurophysiology Laboratory and co-director of the Rose F. Kennedy Intellectual & Developmental Disabilities Research Center (IDDRC) and a related T32 training grant.
Dr. Molholm is interested in how the human brain processes and integrates sensory inputs to impact perception and behavior, and the role of executive functions on these processes. Her work involves characterizing these processes in healthy adults, charting their developmental course over childhood, and translating these findings to understand the neurobiology of developmental disorders, with an emphasis on autism. Non-invasive high-density recordings of the electrical activity of the brain, intracranial recordings in patients, psychophysics and magnetic resonance imaging are her primary tools of investigation. She receives support for her research from NIMH, NSF, and private foundations such as SFARI.
Selected publications
Malcolm, B.R., Foxe, J.J., Butler, J.S., Molholm, S., De Sanctis, P. (2018) Cognitive load reduces the effects of optic flow on gait and electrocortical dynamics during treadmill walking. Journal of neurophysiology. 120 (5), 2246-2259.
Foxe, J.J., Molholm, S., Baudouin, S.J., Wallace, M.T. (2018). Explorations and perspectives on the neurobiological bases of autism spectrum disorder. European Journal of Neuroscience 47 (6), 488-496.
Rimmele, J.M., Gross, J., Molholm, S., Keitel, A. (2018). Brain Oscillations in Human Communication. Frontiers in human neuroscience 12, 39.
Freedman, E.G., Molholm, S., Gray, M.J., Belyusar, D., Foxe, J.J. (2017). Saccade adaptation deficits in developmental dyslexia suggest disruption of cerebellar-dependent learning. Journal of neurodevelopmental disorders 9 (1), 36.
Beker, S., Foxe, J.J., Molholm, S. (2017). Ripe for solution: delayed development of multisensory processing in autism and its remediation. Neuroscience & Biobehavioral Reviews.
Ross, L.A., Del Bene, V.A., Molholm, S., Woo, Y.J., Andrade, G.N., Abrahams, B. S., Foxe, J. J. (2017). Common variation in the autism risk gene CNTNAP2, brain structural connectivity and multisensory speech integration. Brain and language 174, 50-60
Cuppini, C., Ursino, M., Magosso, E., Ross, L., Foxe, J.J., Molholm, S. (2017). A computational analysis of neural mechanisms underlying the maturation of the multisensory speech integration in neurotypical children and those on the autism spectrum.
Malcolm, B., Foxe, J.J., Butler, J.S., Mowrey, W.B., Molholm, S., De Sanctis. (2017). Long-term test-retest reliability of event-related potential (ERP) recordings during treadmill walking using the mobile brain/body imaging (MoBI) approach. Brain Research.
Beker, S., Foxe, J.J., Molholm, S. (2017). Ripe for solution: Delayed development of multisensory. Physiology 81 (4), 440-471.
Ross, L.A., Del Bene, V.A., Molholm, S., Woo, Y.J., Andrade, G.N., Abrahams, B.S., Foxe, J.J. (2017). Common variation in the autism risk gene CNTNAP2, brain structural connecticity and multisensory speech integration. Brain and language 174, 50-60.
Cuppini, C., Ursino, M., Magosso, E., Ross, L.A., Foxe, J.J., Molholm, S. (2017). A computational analysis of neural mechanisms underlying the maturation of multisensory speech integration in neurotypical children and those on the autism spectrum. Frontiers in human neuroscience 11, 518.
Malcolm B.R., Foxe J.J., Butler J.S., Mowrey W.B., Molholm S., De Sanctis P. (2017). Long term test-retest reliability of event-related potential (ERP) recordings during treadmill walking using the mobile brain/body imaging (MoBI) approach. Brain Res. 2017. doi:10.1016/j.brainres.2017.05.021.