from sensory-perceptual representations to cognitive processing

in rett syndrome

This study aims to characterize low-order sensory-perceptual and high-order cognitive processing in females with Rett syndrome toward the development if a neurocognitive biomarker for the condition. We will use event-related potentials (ERPs - a non-invasive way of observing brain activity) to assess whether the brains of Rett patients can detect changes in the duration of a tone, as well as to observe the integrity of brain systems that are involved when a subject actively attends to a stimulus. We hope that eventually we can use these ERPs as biomarkers to assess the effectiveness of therapies and interventions for patients with Rett syndrome.

For more information, contact Douwe Horsthuis at