From sensory-perceptual representations to cognitive processing in rett syndrome

This study aims to characterize low-order sensory-perceptual and high-order cognitive processing in females with Rett syndrome toward the development if a neurocognitive biomarker for the condition. We will use event-related potentials (ERPs - a non-invasive way of observing brain activity) to assess whether the brains of Rett patients can detect changes in the duration of a tone, as well as to observe the integrity of brain systems that are involved when a subject actively attends to a stimulus. We hope that eventually we can use these ERPs as biomarkers to assess the effectiveness of therapies and interventions for patients with Rett syndrome.

For more information, contact Douwe Horsthuis at douwe.horsthuis@einsteinmed.org.

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